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PRKRA and NKRF
Data Source:
BioGRID
(two hybrid, two hybrid)
PRKRA
NKRF
Description
protein activator of interferon induced protein kinase EIF2AK2
NFKB repressing factor
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Perinuclear Region Of Cytoplasm
RISC-loading Complex
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
RNA Binding
Double-stranded RNA Binding
Protein Binding
Enzyme Activator Activity
Enzyme Binding
Identical Protein Binding
Protein Homodimerization Activity
Pre-miRNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
RNA Binding
Protein Binding
Biological Process
Protein Phosphorylation
Immune Response
Negative Regulation Of Cell Population Proliferation
Response To Virus
MiRNA Metabolic Process
Viral Process
Production Of SiRNA Involved In RNA Interference
Pre-miRNA Processing
Cellular Response To Oxidative Stress
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Outer Ear Morphogenesis
Middle Ear Morphogenesis
Skeletal System Morphogenesis
Regulation Of Catalytic Activity
Protein Stabilization
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Inflammatory skin disease (
25574825
)
Multiple sclerosis (OCB status) (
23472185
)
Rapid functional decline in sporadic amyotrophic lateral sclerosis (
26746183
)
Interacting Genes
28 interacting genes:
ADARB1
AGO2
CEBPZ
CEP126
COPS6
DICER1
EHHADH
EIF2AK2
GDF9
LNX1
LYAR
NKRF
PIAS2
POLR2G
RABEPK
RB1
SETDB1
SHC1
SNX5
STAU1
STRBP
TARBP2
TIRAP
TP53
ZFP28
ZMAT3
ZMAT4
ZNF746
12 interacting genes:
ADARB1
DHX15
DHX58
HMOX2
KIFC1
NFKB1
NFKB2
PRKRA
REL
RELA
STAU1
ZNF346
Entrez ID
8575
55922
HPRD ID
04573
02341
Ensembl ID
ENSG00000180228
ENSG00000186416
Uniprot IDs
B4DJC7
O75569
A3F769
O15226
PDB IDs
2DIX
6SH6
6SH7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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