PRKRA and CEBPZ

Data Source:
BioGRID (two hybrid)

		PRKRA	CEBPZ
Description		protein activator of interferon induced protein kinase EIF2AK2	CCAAT enhancer binding protein zeta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex	Nucleus
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding	DNA Binding Transcription Coactivator Activity RNA Binding
	Biological Process	Protein Phosphorylation Immune Response Negative Regulation Of Cell Population Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Skeletal System Morphogenesis Regulation Of Catalytic Activity Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)	Schizophrenia ( 23974872)
Interacting Genes		28 interacting genes: ADARB1 AGO2 CEBPZ CEP126 COPS6 DICER1 EHHADH EIF2AK2 GDF9 LNX1 LYAR NKRF PIAS2 POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 STAU1 STRBP TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZMAT4 ZNF746	16 interacting genes: GSK3B HMOX2 LAG3 LAMTOR3 LTB4R2 LZTR1 MFHAS1 NFYB PCBD1 PRKRA RPS6KA6 RXRG STAT6 TP53 TP73 UBE3A
Entrez ID		8575	10153
HPRD ID		04573	09875
Ensembl ID		ENSG00000180228	ENSG00000115816
Uniprot IDs		B4DJC7 O75569	Q03701
PDB IDs		2DIX
Enriched GO Terms of Interacting Partners?
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