PRKRA and RABEPK

Data Source:
BioGRID (two hybrid)

		PRKRA	RABEPK
Description		protein activator of interferon induced protein kinase EIF2AK2	Rab9 effector protein with kelch motifs
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex	Endosome Cytosol Endosome Membrane Transport Vesicle Trans-Golgi Network Membrane
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding	Protein Binding
	Biological Process	Protein Phosphorylation Immune Response Negative Regulation Of Cell Population Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Skeletal System Morphogenesis Regulation Of Catalytic Activity Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)	Refractive error ( 32231278)
Interacting Genes		28 interacting genes: ADARB1 AGO2 CEBPZ CEP126 COPS6 DICER1 EHHADH EIF2AK2 GDF9 LNX1 LYAR NKRF PIAS2 POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 STAU1 STRBP TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZMAT4 ZNF746	8 interacting genes: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 TRIM55 ZYX
Entrez ID		8575	10244
HPRD ID		04573	09337
Ensembl ID		ENSG00000180228	ENSG00000136933
Uniprot IDs		B4DJC7 O75569	A0A024R8A0 A0A0S2Z4Z1 A0A0S2Z4Z5 Q7Z6M1
PDB IDs		2DIX
Enriched GO Terms of Interacting Partners?
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