NKRF and DHX58

Data Source:
BioGRID (pull down)

		NKRF	DHX58
Description		NFKB repressing factor	DExH-box helicase 58
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific RNA Binding Protein Binding	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Response To Virus Response To Bacterium Viral Process Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways			DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		12 interacting genes: ADARB1 DHX15 DHX58 HMOX2 KIFC1 NFKB1 NFKB2 PRKRA REL RELA STAU1 ZNF346	9 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2
Entrez ID		55922	79132
HPRD ID		02341	13115
Ensembl ID		ENSG00000186416	ENSG00000108771
Uniprot IDs		A3F769 O15226	A0A024R1Y5 Q96C10
PDB IDs		6SH6 6SH7	2RQA 2W4R 3EQT
Enriched GO Terms of Interacting Partners?
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