LMNB2 and FH

Data Source:
BioGRID (two hybrid)

		LMNB2	FH
Description		lamin B2	fumarate hydratase
Image
GO Annotations	Cellular Component	Nuclear Inner Membrane Intermediate Filament Nuclear Membrane	Nucleus Chromosome Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Tricarboxylic Acid Cycle Enzyme Complex Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Fumarate Hydratase Activity Protein Binding
	Biological Process	Biological_process	Tricarboxylic Acid Cycle Fumarate Metabolic Process Malate Metabolic Process DNA Repair Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of Cold-induced Thermogenesis
Pathways			Citric acid cycle (TCA cycle)
Drugs
Diseases			Renal cell carcinoma Multiple cutaneous and uterine leiomyomata Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
GWAS			Daytime sleep phenotypes ( 27126917) Major depressive disorder ( 27479909) Metabolite levels ( 23823483)
Interacting Genes		30 interacting genes: AMOT AMOTL2 CA8 CCDC120 CCDC88B CDC37 EFHC2 FH GOLGA2 LMNA LMNB1 LZTS1 MFAP1 MID2 OVOL1 PIBF1 POU6F2 PPP1R13B PRKCD SVIL TFIP11 THAP1 TMPO TP53BP2 TRIM27 TSGA10IP USP2 WASHC3 ZC2HC1C ZFHX3	17 interacting genes: C11orf49 CCDC102B CCDC57 CCNDBP1 DGCR6 EXOSC5 GRB2 H2AZ1 KLHL6 LMNB2 MDH2 PIM1 POLR1C PRKDC SAT1 TNPO2 TTC19
Entrez ID		84823	2271
HPRD ID		01037	00652
Ensembl ID		ENSG00000176619	ENSG00000091483
Uniprot IDs		Q03252	A0A0S2Z4C3 P07954
PDB IDs		2LLL 5BNW	3E04 5D6B 5UPP 6EBT
Enriched GO Terms of Interacting Partners?
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