TPST2 and SELPLG

Data Source:
HPRD (in vitro)

		TPST2	SELPLG
Description		tyrosylprotein sulfotransferase 2	selectin P ligand
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft
	Molecular Function	Sulfotransferase Activity Protein-tyrosine Sulfotransferase Activity Protein Homodimerization Activity	Virus Receptor Activity Signaling Receptor Binding Protein Binding
	Biological Process	Peptidyl-tyrosine Sulfation Protein Phosphopantetheinylation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6
Pathways		Cytosolic sulfonation of small molecules Gamma carboxylation, hypusine formation and arylsulfatase activation Defective F8 sulfation at Y1699	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)	Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)
Interacting Genes		5 interacting genes: CCR1 CCR8 CMKLR1 GPR1 SELPLG	14 interacting genes: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN
Entrez ID		8459	6404
HPRD ID		07217	02845
Ensembl ID		ENSG00000128294	ENSG00000110876
Uniprot IDs		A0A024R1G9 O60704	Q14242
PDB IDs		3AP1 3AP2 3AP3	1G1S
Enriched GO Terms of Interacting Partners?
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