SELPLG and TPST2

Data Source:
HPRD (in vitro)

		SELPLG	TPST2
Description		selectin P ligand	tyrosylprotein sulfotransferase 2
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GO Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Protein Binding	Sulfotransferase Activity Protein-tyrosine Sulfotransferase Activity Protein Homodimerization Activity
	Biological Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Peptidyl-tyrosine Sulfation Protein Phosphopantetheinylation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways		Cell surface interactions at the vascular wall	Cytosolic sulfonation of small molecules Gamma carboxylation, hypusine formation and arylsulfatase activation Defective F8 sulfation at Y1699
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)	Anti-saccade response ( 29064472) Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN	5 interacting genes: CCR1 CCR8 CMKLR1 GPR1 SELPLG
Entrez ID		6404	8459
HPRD ID		02845	07217
Ensembl ID		ENSG00000110876	ENSG00000128294
Uniprot IDs		Q14242	A0A024R1G9 O60704
PDB IDs		1G1S	3AP1 3AP2 3AP3
Enriched GO Terms of Interacting Partners?
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