SELPLG and SELL

Data Source:
HPRD (in vivo, in vitro)

		SELPLG	SELL
Description		selectin P ligand	selectin L
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GO Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft	Plasma Membrane Integral Component Of Plasma Membrane Secretory Granule Membrane
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Protein Binding	Protease Binding Calcium Ion Binding Protein Binding Heparin Binding Carbohydrate Binding Glycosphingolipid Binding Oligosaccharide Binding
	Biological Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neutrophil Degranulation Regulation Of Immune Response Leukocyte Migration Leukocyte Tethering Or Rolling
Pathways		Cell surface interactions at the vascular wall	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)	Acne (severe) ( 24399259) Amyotrophic lateral sclerosis ( 19451621) Basophil percentage of white cells ( 32888494) Blood protein levels ( 30072576 29875488 28240269) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479)
Interacting Genes		14 interacting genes: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN	16 interacting genes: CD4 CFH EMCN EZR GRB2 MSN MUC7 PODXL PODXL2 PRKCA PRKCQ PRKG1 SELE SELPLG SLC30A2 VCAN
Entrez ID		6404	6402
HPRD ID		02845	07034
Ensembl ID		ENSG00000110876	ENSG00000188404
Uniprot IDs		Q14242	P14151
PDB IDs		1G1S	1KJB 2LGF 3CFW 5VC1
Enriched GO Terms of Interacting Partners?
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