SELPLG and TPST1

Data Source:
HPRD (in vitro)

		SELPLG	TPST1
Description		selectin P ligand	tyrosylprotein sulfotransferase 1
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GO Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Golgi Membrane
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Protein Binding	Sulfotransferase Activity Protein-tyrosine Sulfotransferase Activity Protein Homodimerization Activity
	Biological Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Peptidyl-tyrosine Sulfation Inflammatory Response Protein Phosphopantetheinylation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways		Cell surface interactions at the vascular wall	Cytosolic sulfonation of small molecules Gamma carboxylation, hypusine formation and arylsulfatase activation Defective F8 sulfation at Y1699
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)	Blood protein levels ( 30072576 29875488) Gout ( 22179738)
Interacting Genes		14 interacting genes: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN	6 interacting genes: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG
Entrez ID		6404	8460
HPRD ID		02845	07216
Ensembl ID		ENSG00000110876	ENSG00000169902
Uniprot IDs		Q14242	A0A024RDK9 O60507
PDB IDs		1G1S	5WRI 5WRJ
Enriched GO Terms of Interacting Partners?
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