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KPNA6 and NUP50
Data Source:
BioGRID
(two hybrid)
KPNA6
NUP50
Description
karyopherin subunit alpha 6
nucleoporin 50
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Host Cell
Nuclear Pore
Nucleoplasm
Nuclear Membrane
Host Cell
Molecular Function
Protein Binding
Nuclear Localization Sequence Binding
Nuclear Import Signal Receptor Activity
Protein Binding
Biological Process
NLS-bearing Protein Import Into Nucleus
Viral Genome Replication
Mitigation Of Host Defenses By Symbiont
Positive Regulation Of Transcription By RNA Polymerase II
Maternal Process Involved In Female Pregnancy
Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Viral Life Cycle
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Viral Process
Protein Sumoylation
Viral Transcription
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Mean corpuscular volume (
32888494
)
Interacting Genes
37 interacting genes:
ANKRD11
ANP32A
ANP32B
ARNT
BRCA1
CDKN1B
CREBBP
CSE1L
DCPS
EPAS1
FAM90A1
FRG1BP
GEMIN2
HIF1A
IL1A
JRK
KAT5
KEAP1
KPNB1
LMNA
LMNB1
MAGED1
NMNAT1
NOP2
NUP50
POLR3C
POM121
POU6F2
RAC1
RELB
RNMT
SKP2
SMARCB1
STAT1
STAT3
TAF9
ZNF131
14 interacting genes:
APP
CDKN1B
IPO13
KEAP1
KPNA1
KPNA2
KPNA3
KPNA4
KPNA5
KPNA6
KPNB1
RAN
SRPK2
XPO1
Entrez ID
23633
10762
HPRD ID
09465
05226
Ensembl ID
ENSG00000025800
ENSG00000093000
Uniprot IDs
O60684
A0A024R4X7
B4E2D3
Q9UKX7
PDB IDs
4UAD
2EC1
3TJ3
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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