KPNA6 and GEMIN2

Data Source:
BioGRID (two hybrid)

		KPNA6	GEMIN2
Description		karyopherin subunit alpha 6	gem nuclear organelle associated protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Protein Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Mitigation Of Host Defenses By Symbiont Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Import Into Nucleus
Pathways			snRNP Assembly
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Vitamin D levels ( 28757204)
Interacting Genes		37 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131	34 interacting genes: BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPF SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2
Entrez ID		23633	8487
HPRD ID		09465	03999
Ensembl ID		ENSG00000025800	ENSG00000092208
Uniprot IDs		O60684	O14893
PDB IDs		4UAD	2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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