ANKRD55 and NOXA1

  • Data Source:
  • BioGRID (two hybrid)

ANKRD55

NOXA1

Description ankyrin repeat domain 55 NADPH oxidase activator 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Celiac disease or Rheumatoid arthritis ( 21383967)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • IgA levels ( 28628107)
  • IgG glycosylation ( 23382691)
  • Immature fraction of reticulocytes ( 32888494)
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
  • Lung function (FEV1) ( 30061609)
  • Macular thickness ( 30535121)
  • Monocyte count ( 27863252)
  • Monocyte percentage of white cells ( 32888494)
  • Multiple sclerosis ( 31604244 24076602 27386562)
  • Optic disc size ( 31809533)
  • Pediatric autoimmune diseases ( 26301688)
  • Post-traumatic stress disorder ( 27167565)
  • Reticulocyte fraction of red cells ( 32888494)
  • Rheumatoid arthritis ( 30423114 30572963 23143596 24390342 20453842)
  • Rheumatoid arthritis (ACPA-negative) ( 23143596)
  • Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
  • Sero-negative rheumatoid arthritis ( 28706201)
  • Triglycerides ( 20686565)
  • Type 2 diabetes ( 27189021 22885922 26961502 29358691 30297969 26818947 32499647 30718926 28869590)
  • Urate levels ( 23263486)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes 22 interacting genes: ABI2 ANKS1A BACH2 BANP BOLA2 BOLA2B CABP5 CFAP206 CLIC3 FHL2 FHL5 FRS3 HGS HSF2BP NCK2 NOXA1 PFDN5 PTK6 TEKT4 TRIM23 ZMYND19 ZSCAN1 57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620
Entrez ID 79722 10811
HPRD ID 07758 17644
Ensembl ID ENSG00000164512 ENSG00000188747
Uniprot IDs Q3KP44 Q86UR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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