NOXA1 and NADSYN1

Data Source:
BioGRID (two hybrid)

		NOXA1	NADSYN1
Description		NADPH oxidase activator 1	NAD synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Cytoplasm Cytosol
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	NAD+ Synthase (glutamine-hydrolyzing) Activity Glutaminase Activity Protein Binding ATP Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	NAD Biosynthetic Process NAD Metabolic Process 'de Novo' NAD Biosynthetic Process
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping	Nicotinate metabolism
Drugs			Glutamic acid
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Systemic lupus erythematosus ( 26502338) Vitamin D insufficiency ( 20541252) Vitamin D levels ( 29343764 20418485) Vitamin D levels (dietary vitamin D intake interaction) ( 29343764)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	13 interacting genes: ANKS1A COL8A1 CREB5 CUTC FRS3 GPANK1 HGS HOXC8 MYO15B NOXA1 NTAQ1 TFG UPF1
Entrez ID		10811	55191
HPRD ID		17644	16309
Ensembl ID		ENSG00000188747	ENSG00000172890
Uniprot IDs		Q86UR1	Q6IA69
PDB IDs			6OFB
Enriched GO Terms of Interacting Partners?
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