NOXA1 and TGS1

Data Source:
BioGRID (two hybrid)

		NOXA1	TGS1
Description		NADPH oxidase activator 1	trimethylguanosine synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Small Nuclear Ribonucleoprotein Complex
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	Protein Binding RNA Methyltransferase Activity RNA Trimethylguanosine Synthase Activity
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Spliceosomal SnRNP Assembly 7-methylguanosine RNA Capping Regulation Of Lipid Metabolic Process Ribonucleoprotein Complex Biogenesis 7-methylguanosine Cap Hypermethylation
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping	RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression snRNP Assembly PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock
Drugs
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Gut microbiota (bacterial taxa) ( 27723756) Height ( 18391951) Serum thyroid-stimulating hormone levels ( 24852370)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	9 interacting genes: ANKRD28 COIL CREBBP EED EP300 HNF4A NCOA6 NOXA1 ZNF76
Entrez ID		10811	96764
HPRD ID		17644	07567
Ensembl ID		ENSG00000188747	ENSG00000137574
Uniprot IDs		Q86UR1	Q96RS0
PDB IDs			3EGI 3GDH
Enriched GO Terms of Interacting Partners?
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