NOXA1 and ZNF620

Data Source:
BioGRID (two hybrid)

		NOXA1	ZNF620
Description		NADPH oxidase activator 1	zinc finger protein 620
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Nucleus
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping	Generic Transcription Pathway
Drugs
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Neuroticism ( 29255261)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	72 interacting genes: ABLIM3 ATG9A BFSP2 BOLA2 BOLA2B C1orf216 C22orf39 CABP5 CARD9 CCDC102B CCDC6 CCHCR1 CCNC CDCA7L CDKN2D CHAF1A CIB3 CINP CLIC3 CTNNA3 DGCR6L DTX2 EAF1 EEF2KMT EIF4A2 EPM2AIP1 EXOSC5 FHL2 GAS8 GLYCTK GRB2 GYS1 IGFN1 IL16 JRK KCTD9 LMO1 LMO3 MAGOHB MAP2K5 METTL21A MFAP1 MISP MLX MYOZ3 NDOR1 NME7 NOXA1 OAZ3 PIBF1 PIK3R3 PLOD3 POLE2 RIPPLY1 RUSC1 SAAL1 SART3 SLIT1 SNAPC3 TENT5B TPM2 TRAF4 TRIM10 TRIM50 TSEN15 TSR2 USP20 ZBTB16 ZFHX3 ZIC1 ZNF24 ZNF648
Entrez ID		10811	253639
HPRD ID		17644	15878
Ensembl ID		ENSG00000188747	ENSG00000177842
Uniprot IDs		Q86UR1	Q6ZNG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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