NOXA1 and TCF19

Data Source:
BioGRID (two hybrid)

		NOXA1	TCF19
Description		NADPH oxidase activator 1	transcription factor 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol NADPH Oxidase Complex	Nucleus
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding	DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression
Pathways		RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic hepatitis B infection ( 25802187 23760081) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Marginal zone lymphoma ( 25569183) Multiple myeloma ( 23955597) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Type 2 diabetes ( 24509480 30718926) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	19 interacting genes: APP BLZF1 CEP76 DNAJA3 GOLGA2 H3-4 H4-16 HOXA1 HSF2BP LZTR1 NFKBID NOXA1 PDLIM7 PFDN5 PRKAB2 RHOH TRIB3 UBE3A ZNF474
Entrez ID		10811	6941
HPRD ID		17644	15986
Ensembl ID		ENSG00000188747	ENSG00000137310
Uniprot IDs		Q86UR1	A0A1U9X8M7 Q9Y242
PDB IDs
Enriched GO Terms of Interacting Partners?
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