UQCRB and ACAP1

Data Source:
BioGRID (two hybrid)

		UQCRB	ACAP1
Description		ubiquinol-cytochrome c reductase binding protein	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III	Membrane Recycling Endosome Membrane
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration	Protein Transport Positive Regulation Of GTPase Activity
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Huntington's disease progression ( 28642124)	Autoimmune thyroid disease ( 32581359) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 33536424) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7	11 interacting genes: AKT1 FCHSD2 GRB2 IFFO1 ITGB1 NEBL RABGAP1L SH3RF1 TFRC UQCRB VAMP3
Entrez ID		7381	9744
HPRD ID		11770	08474
Ensembl ID		ENSG00000156467	ENSG00000072818
Uniprot IDs		P14927	Q15027
PDB IDs		5XTE 5XTH 5XTI	3JUE 3T9K 4CKG 4CKH 4F1P 4NSW 5H3D
Enriched GO Terms of Interacting Partners?
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