UQCRB and MAGEA1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UQCRB	MAGEA1
Description		ubiquinol-cytochrome c reductase binding protein	MAGE family member A1
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Huntington's disease progression ( 28642124)
Interacting Genes		9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7	25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		7381	4100
HPRD ID		11770	02059
Ensembl ID		ENSG00000156467	ENSG00000198681
Uniprot IDs		P14927	P43355
PDB IDs		5XTE 5XTH 5XTI	1W72 3BO8
Enriched GO Terms of Interacting Partners?
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