UQCRB and ACCS

Data Source:
BioGRID (two hybrid)

		UQCRB	ACCS
Description		ubiquinol-cytochrome c reductase binding protein	1-aminocyclopropane-1-carboxylate synthase homolog (inactive)
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III
	Molecular Function	Protein Binding	Protein Binding 1-aminocyclopropane-1-carboxylate Synthase Activity Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration	1-aminocyclopropane-1-carboxylate Biosynthetic Process
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2	Vinylglycine
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Huntington's disease progression ( 28642124)	IgA nephropathy ( 26028593)
Interacting Genes		9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7	2 interacting genes: FBF1 UQCRB
Entrez ID		7381	84680
HPRD ID		11770	10524
Ensembl ID		ENSG00000156467	ENSG00000110455
Uniprot IDs		P14927	A0A0S2Z622 Q96QU6
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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