Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
UBE3A and DAZAP2
Data Source:
BioGRID
(two hybrid)
UBE3A
DAZAP2
Description
ubiquitin protein ligase E3A
DAZ associated protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Proteasome Complex
Nucleus
Cytosol
Cytoplasm
Nuclear Speck
Protein-containing Complex
Molecular Function
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Receptor Tyrosine Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Identical Protein Binding
Protein Serine/threonine Kinase Activator Activity
WW Domain Binding
Biological Process
Ovarian Follicle Development
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Brain Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Androgen Receptor Signaling Pathway
Positive Regulation Of Protein Ubiquitination
Response To Progesterone
Sperm Entry
Response To Cocaine
Response To Hydrogen Peroxide
Regulation Of Circadian Rhythm
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Progesterone Receptor Signaling Pathway
Protein Autoubiquitination
Prostate Gland Growth
Negative Regulation Of Dendritic Spine Morphogenesis
Protein K48-linked Ubiquitination
Positive Regulation Of Golgi Lumen Acidification
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS
Cardiac hypertrophy (
21348951
)
Gene methylation in lung tissue (
25713168
)
Obesity-related traits (
23251661
)
Interacting Genes
125 interacting genes:
ACTA2
ACTB
ACTBL2
ACTR3
ADRM1
AFG3L1P
AFTPH
AHSP
ANXA1
APP
AR
ARC
ARHGDIB
ASAP3
ATG9A
BARD1
BLK
BPY2
BPY2B
BPY2C
BRCA1
C11orf49
CALR
CDK1
CDK4
CDKN1B
CEBPZ
CGGBP1
CTNNB1
DAZAP2
DLG1
E2F1
EAPP
EID1
EIF4G1
FAF2
GFAP
GTF3C1
HBA1
HPCAL4
HSP90AB1
HSPA4
HSPA5
JADE1
KLHL38
KRT1
KRT5
KRT7
KRT9
LCK
MAGEA12
MAGEA8
MAPK1
MARF1
MCM6
MCM7
MDM1
MDM2
MEOX2
NBPF14
NDUFA13
NELFCD
NOMO2
NR4A3
PARVA
PAX5
PAX6
PDE1B
PDIA3
PDIA6
PGR
PML
POLE4
PRAG1
PRDX1
PRKACA
PRMT5
PSAP
PTCD3
RAD23A
RAD23B
RARA
RMI1
RPS15A
RYBP
SACS
SCAMP1
SCRIB
SHBG
SIRT6
SMAD9
SNAPC3
SOD1
SPINK1
SUMO3
TALDO1
TAT
TBC1D14
TCF19
TMEM14B
TP53
TP53BP2
TRIM65
TSC2
TTC23L
TTC3
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2G1
UBE2G2
UBE2L3
UBE2L6
UBE2N
UBQLN1
UBQLN2
WBP2
YOD1
YWHAE
YWHAG
YWHAZ
ZNF250
ZNF446
164 interacting genes:
AATF
ACOT7
AOC1
ARID5A
ATXN1
ATXN1L
BAG3
BATF2
BHLHE40
C1orf94
CALCOCO2
CAMK2A
CAPN15
CCDC120
CDK4
CELF5
CEP70
CLASRP
COL4A2
COL4A5
CXCL12
DAB1
DAZ1
DAZL
DCUN1D1
DESI1
DTX2
EPN1
EPN2
EPN3
ESRP1
EXD3
FAM168A
FAM83A
FBN3
FOXH1
GGA3
GPS2
GPSM1
HEY1
HGS
HIP1
INCA1
KLHL42
KRTAP19-1
KRTAP19-3
KRTAP19-5
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP6-2
KRTAP8-1
LASP1
LGALS9
LITAF
LMO2
MAGED1
MAPK1IP1L
MED31
MINDY1
MINDY3
MTURN
MYEOV
MYOZ3
NDUFA5
NEDD4
NEDD4L
NOC4L
NOTCH1
OPTN
OTUB2
OTUD7B
OTULIN
PATZ1
PDIK1L
PEF1
PITX2
PLEKHB2
PLEKHF2
PLSCR1
PLSCR4
POGZ
POLI
PROP1
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR34
RABGEF1
RAD18
RAD23A
RAMAC
RBFOX1
RBFOX2
RBM11
RBM24
RBM43
RBPMS
RHOXF2
RNF115
RNF208
RNF44
ROR2
RPS27A
SEPTIN2
SMAP2
SMURF2
SNRPC
SOX10
SOX6
SQSTM1
STAM2
STAT6
TAX1BP1
TBX6
TCF7L2
TENT5B
TENT5C
TEX37
TFG
TIAL1
TLE1
TLE5
TNIP1
TNIP3
TOLLIP
TOM1
UBA52
UBAC1
UBAP2
UBASH3A
UBASH3B
UBB
UBC
UBE2D4
UBE2E2
UBE2E3
UBE2V1
UBE3A
UBQLN1
UBQLN2
UBQLN4
UBXN6
UBXN7
USP13
USP5
VENTX
VEZF1
VHLL
VPS37C
WDR73
WWOX
WWP1
YOD1
ZBTB32
ZC3H10
ZFAND2A
ZFAND2B
ZFYVE9
ZNF34
ZNF581
Entrez ID
7337
9802
HPRD ID
03375
08463
Ensembl ID
ENSG00000114062
ENSG00000183283
Uniprot IDs
Q05086
Q9H2G0
A0A024R110
Q15038
PDB IDs
1C4Z
1D5F
1EQX
2KR1
4GIZ
4XR8
6SJV
6SLM
6TGK
6U19
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?