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UBE3A and RAD23A
Data Source:
BioGRID
(two hybrid)
UBE3A
RAD23A
Description
ubiquitin protein ligase E3A
RAD23 homolog A, nucleotide excision repair protein
Image
GO Annotations
Cellular Component
Proteasome Complex
Nucleus
Cytosol
Proteasome Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Protein-containing Complex
Centriolar Satellite
Intracellular Membrane-bounded Organelle
Molecular Function
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Kinase Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Binding
Proteasome Binding
Ubiquitin-specific Protease Binding
Biological Process
Ovarian Follicle Development
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Brain Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Androgen Receptor Signaling Pathway
Positive Regulation Of Protein Ubiquitination
Response To Progesterone
Sperm Entry
Response To Cocaine
Response To Hydrogen Peroxide
Regulation Of Circadian Rhythm
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Progesterone Receptor Signaling Pathway
Protein Autoubiquitination
Prostate Gland Growth
Negative Regulation Of Dendritic Spine Morphogenesis
Protein K48-linked Ubiquitination
Positive Regulation Of Golgi Lumen Acidification
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Nucleotide-excision Repair
Viral Process
Protein Deubiquitination
Protein Destabilization
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Cell Cycle
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Josephin domain DUBs
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Drugs
Diseases
Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS
Cardiac hypertrophy (
21348951
)
Gene methylation in lung tissue (
25713168
)
Obesity-related traits (
23251661
)
Clozapine-induced agranulocytosis (
25187353
)
Interacting Genes
125 interacting genes:
ACTA2
ACTB
ACTBL2
ACTR3
ADRM1
AFG3L1P
AFTPH
AHSP
ANXA1
APP
AR
ARC
ARHGDIB
ASAP3
ATG9A
BARD1
BLK
BPY2
BPY2B
BPY2C
BRCA1
C11orf49
CALR
CDK1
CDK4
CDKN1B
CEBPZ
CGGBP1
CTNNB1
DAZAP2
DLG1
E2F1
EAPP
EID1
EIF4G1
FAF2
GFAP
GTF3C1
HBA1
HPCAL4
HSP90AB1
HSPA4
HSPA5
JADE1
KLHL38
KRT1
KRT5
KRT7
KRT9
LCK
MAGEA12
MAGEA8
MAPK1
MARF1
MCM6
MCM7
MDM1
MDM2
MEOX2
NBPF14
NDUFA13
NELFCD
NOMO2
NR4A3
PARVA
PAX5
PAX6
PDE1B
PDIA3
PDIA6
PGR
PML
POLE4
PRAG1
PRDX1
PRKACA
PRMT5
PSAP
PTCD3
RAD23A
RAD23B
RARA
RMI1
RPS15A
RYBP
SACS
SCAMP1
SCRIB
SHBG
SIRT6
SMAD9
SNAPC3
SOD1
SPINK1
SUMO3
TALDO1
TAT
TBC1D14
TCF19
TMEM14B
TP53
TP53BP2
TRIM65
TSC2
TTC23L
TTC3
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2G1
UBE2G2
UBE2L3
UBE2L6
UBE2N
UBQLN1
UBQLN2
WBP2
YOD1
YWHAE
YWHAG
YWHAZ
ZNF250
ZNF446
76 interacting genes:
A2M
ADRM1
ANKRD40
ATXN3
ATXN7
CCNA2
CDC37
CHEK1
CNTROB
CREBBP
DAZAP2
DBI
ECSIT
EP300
EWSR1
FILIP1
GTF2H1
HSPB1
IFIT3
IFIT5
KRTAP12-2
LOXL4
MAP3K1
MAST1
MDM2
MINDY3
MKRN1
MPG
NEDD8
NGLY1
NUTM2F
PDE6D
PHAX
PI4K2A
PRKN
PSEN1
PSMC5
PSMD4
RABGEF1
REL
RNF115
RNF32
RNF41
RPN1
RPS27A
SH3RF1
SMURF1
SQSTM1
TNFAIP3
TRAF2
TRAF3
TRAF5
TRAF6
TRIM39
TRIM50
TRIM54
TRIM55
TRIM8
TRIP6
UBA52
UBB
UBC
UBE3A
UBE4B
UBL7
UBQLN2
UBQLN4
UBXN1
UIMC1
USP25
VAV2
XPC
ZBTB26
ZBTB44
ZBTB8A
ZFAND6
Entrez ID
7337
5886
HPRD ID
03375
07191
Ensembl ID
ENSG00000114062
ENSG00000179262
Uniprot IDs
Q05086
Q9H2G0
A0A024R7G8
A8K1J3
P54725
PDB IDs
1C4Z
1D5F
1EQX
2KR1
4GIZ
4XR8
6SJV
6SLM
6TGK
6U19
1DV0
1F4I
1IFY
1OQY
1P98
1P9D
1QZE
1TP4
1ZO6
2WYQ
5XBO
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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