TGM1 and SULT4A1

Data Source:
BioGRID (two hybrid)

		TGM1	SULT4A1
Description		transglutaminase 1	sulfotransferase family 4A member 1
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GO Annotations	Cellular Component	Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Sulfotransferase Activity Identical Protein Binding
	Biological Process	Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Protein Phosphopantetheinylation Keratinocyte Differentiation Cell Envelope Organization Positive Regulation Of Cell Cycle Cornification	Biological_process Steroid Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		Formation of the cornified envelope	Cytosolic sulfonation of small molecules
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS			Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes		34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4	6 interacting genes: AKT1 MAPK3 MAPK8IP3 POT1 PTPA TGM1
Entrez ID		7051	25830
HPRD ID		01824	07462
Ensembl ID		ENSG00000092295	ENSG00000130540
Uniprot IDs		P22735	B7Z2E1 Q9BR01
PDB IDs		2XZZ	1ZD1
Enriched GO Terms of Interacting Partners?
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