TGM1 and VASN

Data Source:
BioGRID (two hybrid)

		TGM1	VASN
Description		transglutaminase 1	vasorin
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome	Extracellular Space Mitochondrion Lysosomal Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Cadherin Binding Transforming Growth Factor Beta Binding
	Biological Process	Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Protein Phosphopantetheinylation Keratinocyte Differentiation Cell Envelope Organization Positive Regulation Of Cell Cycle Cornification	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Hypoxia Cellular Response To Redox State
Pathways		Formation of the cornified envelope
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS			Erectile dysfunction ( 30583798) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4	53 interacting genes: ADAMTSL4 AQP3 CIB4 CYSRT1 GRN GUCD1 HOXA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2C LCE2D LCE4A LNX1 MDFI MEOX2 MTUS2 NBPF19 NOTCH2NLA NR4A3 RGS17 RGS19 RGS20 RNF31 SMCP SSC4D TGFB1 TGFB2 TGFB3 TGM1 TRIP6 VWC2
Entrez ID		7051	114990
HPRD ID		01824	10587
Ensembl ID		ENSG00000092295	ENSG00000168140
Uniprot IDs		P22735	Q6EMK4
PDB IDs		2XZZ
Enriched GO Terms of Interacting Partners?
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