SULT4A1 and TGM1

Data Source:
BioGRID (two hybrid)

		SULT4A1	TGM1
Description		sulfotransferase family 4A member 1	transglutaminase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Sulfotransferase Activity Identical Protein Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Biological_process Steroid Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Protein Phosphopantetheinylation Keratinocyte Differentiation Cell Envelope Organization Positive Regulation Of Cell Cycle Cornification
Pathways		Cytosolic sulfonation of small molecules	Formation of the cornified envelope
Drugs
Diseases			Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes		6 interacting genes: AKT1 MAPK3 MAPK8IP3 POT1 PTPA TGM1	34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4
Entrez ID		25830	7051
HPRD ID		07462	01824
Ensembl ID		ENSG00000130540	ENSG00000092295
Uniprot IDs		B7Z2E1 Q9BR01	P22735
PDB IDs		1ZD1	2XZZ
Enriched GO Terms of Interacting Partners?
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