TGM1 and C1QTNF1

Data Source:
BioGRID (two hybrid)

		TGM1	C1QTNF1
Description		transglutaminase 1	C1q and TNF related 1
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome	Collagen Trimer Extracellular Space Integral Component Of Plasma Membrane
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Collagen Binding Identical Protein Binding
	Biological Process	Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Protein Phosphopantetheinylation Keratinocyte Differentiation Cell Envelope Organization Positive Regulation Of Cell Cycle Cornification	Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Platelet Activation Positive Regulation Of Gene Expression Regulation Of Glucose Metabolic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Platelet Aggregation Positive Regulation Of Aldosterone Secretion
Pathways		Formation of the cornified envelope
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS
Interacting Genes		34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4	11 interacting genes: AVPR2 C14orf119 C1QTNF6 CACNA1A LMNA LNX1 PRPF31 SGTA TGM1 UBL5 UBQLN4
Entrez ID		7051	114897
HPRD ID		01824	12714
Ensembl ID		ENSG00000092295	ENSG00000173918
Uniprot IDs		P22735	A0A0C4DFP7 A0A3B0J271 Q9BXJ1
PDB IDs		2XZZ
Enriched GO Terms of Interacting Partners?
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