TAC3 and FEZ1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TAC3	FEZ1
Description		tachykinin precursor 3	fasciculation and elongation protein zeta 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Microtubule Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Positive Regulation Of Blood Pressure	Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Positive Regulation Of Neuron Differentiation Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Mitochondrion Morphogenesis Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Copper
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Red cell distribution width ( 28957414) Schizophrenia ( 25056061)	Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		12 interacting genes: CCDC90B ELP1 FEZ1 GPRASP1 PRB1 PRH1 PTN TACR1 TACR2 TACR3 UBC UBR1	57 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		6866	9638
HPRD ID		08877	09212
Ensembl ID		ENSG00000166863	ENSG00000149557
Uniprot IDs		A0A024RB47 A0A024RB97 Q9UHF0	Q99689
PDB IDs		1P9F
Enriched GO Terms of Interacting Partners?
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