TAC3 and TACR3

Data Source:
HPRD (in vivo, in vitro)

		TAC3	TACR3
Description		tachykinin precursor 3	tachykinin receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Membrane Neuronal Cell Body Membrane Sperm Midpiece
	Molecular Function	Signaling Receptor Binding Protein Binding	Tachykinin Receptor Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Positive Regulation Of Blood Pressure	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Aging Positive Regulation Of Heart Rate Response To Estradiol Regulation Of Dopamine Metabolic Process Response To Cocaine Hyperosmotic Salinity Response Response To Morphine Positive Regulation Of Blood Pressure Regulation Of Feeding Behavior Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events	Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Copper	Osanetant Talnetant Pavinetant
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)	Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Red cell distribution width ( 28957414) Schizophrenia ( 25056061)	Chronotype ( 30696823) Heel bone mineral density ( 30598549) Height ( 31562340) Menarche (age at onset) ( 27182965 25231870) Rosacea symptom severity ( 29771307) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		12 interacting genes: CCDC90B ELP1 FEZ1 GPRASP1 PRB1 PRH1 PTN TACR1 TACR2 TACR3 UBC UBR1	4 interacting genes: GPRASP1 TAC1 TAC3 TAC4
Entrez ID		6866	6870
HPRD ID		08877	01209
Ensembl ID		ENSG00000166863	ENSG00000169836
Uniprot IDs		A0A024RB47 A0A024RB97 Q9UHF0	P29371
PDB IDs		1P9F
Enriched GO Terms of Interacting Partners?
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