TAC3 and TACR2

Data Source:
HPRD (in vivo)

		TAC3	TACR2
Description		tachykinin precursor 3	tachykinin receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Sperm Flagellum Sperm Head Sperm Midpiece
	Molecular Function	Signaling Receptor Binding Protein Binding	Tachykinin Receptor Activity Protein Binding Substance K Receptor Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Positive Regulation Of Blood Pressure	Muscle Contraction G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Excretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Operant Conditioning Positive Regulation Of Vascular Permeability Response To Electrical Stimulus Prolactin Secretion Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events	Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Copper	Saredutant
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Red cell distribution width ( 28957414) Schizophrenia ( 25056061)
Interacting Genes		12 interacting genes: CCDC90B ELP1 FEZ1 GPRASP1 PRB1 PRH1 PTN TACR1 TACR2 TACR3 UBC UBR1	5 interacting genes: GPRASP1 MTDH TAC1 TAC3 TAC4
Entrez ID		6866	6865
HPRD ID		08877	01207
Ensembl ID		ENSG00000166863	ENSG00000075073
Uniprot IDs		A0A024RB47 A0A024RB97 Q9UHF0	P21452
PDB IDs		1P9F
Enriched GO Terms of Interacting Partners?
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