TACR2 and TAC3

Data Source:
HPRD (in vivo)

		TACR2	TAC3
Description		tachykinin receptor 2	tachykinin precursor 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Sperm Flagellum Sperm Head Sperm Midpiece	Extracellular Region Extracellular Space
	Molecular Function	Tachykinin Receptor Activity Protein Binding Substance K Receptor Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Muscle Contraction G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Excretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Operant Conditioning Positive Regulation Of Vascular Permeability Response To Electrical Stimulus Prolactin Secretion Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Flagellated Sperm Motility	G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Positive Regulation Of Blood Pressure
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events	Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Saredutant	Copper
Diseases			Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Red cell distribution width ( 28957414) Schizophrenia ( 25056061)
Interacting Genes		5 interacting genes: GPRASP1 MTDH TAC1 TAC3 TAC4	12 interacting genes: CCDC90B ELP1 FEZ1 GPRASP1 PRB1 PRH1 PTN TACR1 TACR2 TACR3 UBC UBR1
Entrez ID		6865	6866
HPRD ID		01207	08877
Ensembl ID		ENSG00000075073	ENSG00000166863
Uniprot IDs		P21452	A0A024RB47 A0A024RB97 Q9UHF0
PDB IDs			1P9F
Enriched GO Terms of Interacting Partners?
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