MTMR9 and MEI4

Data Source:
BioGRID (two hybrid)

		MTMR9	MEI4
Description		myotubularin related protein 9	meiotic double-stranded break formation protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Membrane Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Lateral Element
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Binding Protein Phosphatase Binding Enzyme Regulator Activity	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Negative Regulation Of Autophagy Positive Regulation Of Phosphatase Activity Phosphatidylinositol Dephosphorylation Protein Stabilization Regulation Of Phosphatidylinositol Dephosphorylation	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the late endosome membrane Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Brain morphology (MOSTest) ( 32665545) Essential hypertension (time to event) ( 32589924) Extraversion ( 27918536) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General factor of neuroticism ( 30867560) Processed meat consumption ( 32066663) Refractive error ( 32231278) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170)	Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Macular thickness ( 30535121)
Interacting Genes		26 interacting genes: AATK DEPDC5 EMILIN1 ERBB3 ERBB4 EWSR1 FAM169A GRAMD4 INCA1 KDM1A KIAA1328 KRT27 LNX1 MEI4 MOS MTMR6 MTMR7 MTMR8 NECAB2 NMI PTK7 PTPN3 ROR2 SPG21 VAC14 ZNF655	36 interacting genes: AFMID BAG4 C19orf25 C1orf109 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C
Entrez ID		66036	101928601
HPRD ID		09377
Ensembl ID		ENSG00000104643	ENSG00000269964
Uniprot IDs		Q96QG7	A8MW99
PDB IDs
Enriched GO Terms of Interacting Partners?
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