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TSPYL2 and LMO2
Data Source:
BioGRID
(two hybrid)
TSPYL2
LMO2
Description
TSPY like 2
LIM domain only 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Nucleoplasm
Transcription Regulator Complex
Molecular Function
RDNA Binding
Chromatin Binding
Protein Binding
Histone Binding
RNA Polymerase II Activating Transcription Factor Binding
Transcription Coregulator Binding
Transcription Coactivator Activity
Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
Biological Process
Nucleosome Assembly
Cell Cycle
Negative Regulation Of DNA Replication
Regulation Of Signal Transduction
Negative Regulation Of Cell Growth
IRE1-mediated Unfolded Protein Response
Negative Regulation Of Cell Cycle
Regulation Of Protein Kinase Activity
Multicellular Organism Development
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
XBP1(S) activates chaperone genes
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS
Cognitive performance (
19734545
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Iron status biomarkers (transferrin saturation) (
28334935
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
46 interacting genes:
ABT1
AEBP2
APTX
CASK
CCNB1
CDK1
CDK2
CDK4
CEP19
COIL
CREBBP
CSNK2A1
EEF1A1
GFI1B
H2BC15
HMGXB4
INO80B
KMT5B
LMO2
LNX1
MCRS1
NOL12
NOP53
PHF19
RBM15
RNF151
RPS25
SIRT6
SNIP1
TBC1D26
TMA16
TNNT1
TSPYL1
XAGE1A
XAGE1B
ZBTB24
ZBTB48
ZFP1
ZFP91
ZNF280C
ZNF286A
ZNF329
ZNF524
ZNF687
ZNF775
ZNF835
188 interacting genes:
ABI2
ADAMTSL4
AFDN
AGTRAP
AIMP2
ALDH6A1
ARHGEF5
ARID5A
ARNT2
AXIN1
BANP
BCAS2
BEX2
BLZF1
BYSL
C1orf109
C1orf94
CALCOCO2
CBY2
CCDC33
CDC25A
CDC5L
CDX4
CLHC1
CMTM5
CORO1A
CORO1C
DAZAP2
DBF4B
DDIT3
DMRT3
DRAP1
DYDC1
EFHC1
EFHC2
EHMT2
EIF3B
EIF4EBP1
ELF2
ENKD1
ERBIN
FAAP20
FAM214B
FAM228A
FAM90A1
FHL3
FHL5
GAS8
GATA1
GATA2
GATA3
GFAP
GMEB2
GOLGA2
GRB2
HDAC5
HNRNPC
HNRNPM
HOOK1
ICA1L
IFT43
IHO1
IKZF1
IKZF3
INCA1
ISL1
ISY1
KANK2
KAZN
KDM5A
KIF2A
KIF3B
KPRP
KRT15
KRT34
KRT40
KRT75
KRT80
KRTAP10-7
LDB1
LDB2
LDOC1
LMO4
LMOD3
LYL1
LZTS1
LZTS2
MAGEA8
MAPRE1
MAPRE2
MAPRE3
MBIP
MISP
MRFAP1L1
MSN
MTUS2
MYOZ3
N4BP2L2
NCAPH2
NDOR1
NDUFAB1
NDUFB7
NFKBID
NHLH1
NIF3L1
NOTCH2NLA
NOXA1
NSMF
NTAQ1
NUP62
NUTM1
PATZ1
PAX9
PBX4
PDE9A
PHC2
POLR2G
PPP1R32
PRDM6
PRKG1
PSMA1
RBBP8
RCN1
REL
RELA
RINT1
RLIM
ROCK1
RTL8C
RUSC1
SAXO1
SGTB
SKP1
SMAD2
SMUG1
SNAPC5
SOX5
SP1
SSX2IP
STAT1
STAT3
STIP1
TAL1
TAL2
TBX2
TCP10L
TEKT3
TFIP11
TFPT
THAP6
TLE5
TLX3
TRIB3
TRIM23
TRIM54
TRIM55
TRIM63
TRIP6
TSC1
TSC22D4
TSEN15
TSEN54
TSGA10IP
TSPYL2
TSSK3
TUFT1
UBA6
UBASH3B
UBE2I
USH1G
VBP1
VEZF1
VMAC
WASF1
WASHC1
YOD1
YPEL3
ZFP64
ZMYND12
ZNF185
ZNF19
ZNF24
ZNF250
ZNF34
ZNF410
ZNF641
ZNF655
ZNF688
Entrez ID
64061
4005
HPRD ID
06713
01586
Ensembl ID
ENSG00000184205
ENSG00000135363
Uniprot IDs
Q9H2G4
P25791
PDB IDs
2XJY
2XJZ
2YPA
4KFZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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