LMO2 and NFKBID

Data Source:
BioGRID (two hybrid)

		LMO2	NFKBID
Description		LIM domain only 2	NFKB inhibitor delta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex	Nucleus
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Binding Transcription Coactivator Activity Protein Binding BHLH Transcription Factor Binding Metal Ion Binding	Protein Binding
	Biological Process	Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation	Inflammatory Response Regulation Of Gene Expression T Cell Receptor Signaling Pathway Positive Regulation Of T-helper 17 Cell Differentiation
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cognitive performance ( 19734545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252)
Interacting Genes		188 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 ARHGEF5 ARID5A ARNT2 AXIN1 BANP BCAS2 BEX2 BLZF1 BYSL C1orf109 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DMRT3 DRAP1 DYDC1 EFHC1 EFHC2 EHMT2 EIF3B EIF4EBP1 ELF2 ENKD1 ERBIN FAAP20 FAM214B FAM228A FAM90A1 FHL3 FHL5 GAS8 GATA1 GATA2 GATA3 GFAP GMEB2 GOLGA2 GRB2 HDAC5 HNRNPC HNRNPM HOOK1 ICA1L IFT43 IHO1 IKZF1 IKZF3 INCA1 ISL1 ISY1 KANK2 KAZN KDM5A KIF2A KIF3B KPRP KRT15 KRT34 KRT40 KRT75 KRT80 KRTAP10-7 LDB1 LDB2 LDOC1 LMO4 LMOD3 LYL1 LZTS1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MISP MRFAP1L1 MSN MTUS2 MYOZ3 N4BP2L2 NCAPH2 NDOR1 NDUFAB1 NDUFB7 NFKBID NHLH1 NIF3L1 NOTCH2NLA NOXA1 NSMF NTAQ1 NUP62 NUTM1 PATZ1 PAX9 PBX4 PDE9A PHC2 POLR2G PPP1R32 PRDM6 PRKG1 PSMA1 RBBP8 RCN1 REL RELA RINT1 RLIM ROCK1 RTL8C RUSC1 SAXO1 SGTB SKP1 SMAD2 SMUG1 SNAPC5 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TBX2 TCP10L TEKT3 TFIP11 TFPT THAP6 TLE5 TLX3 TRIB3 TRIM23 TRIM54 TRIM55 TRIM63 TRIP6 TSC1 TSC22D4 TSEN15 TSEN54 TSGA10IP TSPYL2 TSSK3 TUFT1 UBA6 UBASH3B UBE2I USH1G VBP1 VEZF1 VMAC WASF1 WASHC1 YOD1 YPEL3 ZFP64 ZMYND12 ZNF185 ZNF19 ZNF24 ZNF250 ZNF34 ZNF410 ZNF641 ZNF655 ZNF688	110 interacting genes: ADAMTSL4 ANXA11 ARHGEF2 BEX2 C1orf109 C1orf94 C4orf45 CCHCR1 CRYBA2 CTRC CYB5R2 DDX25 DMRT3 DTX3 EFHC2 ELOA ESR2 FAAP20 FAM107A FARS2 FOXI1 GADD45GIP1 GFAP GIGYF1 GLYCTK GPANK1 GRB10 HDAC4 HNRNPF HNRNPH1 HOXA1 HOXB5 HOXC8 HOXC9 HOXD3 HSBP1L1 IHO1 IKZF3 INCA1 IRX6 KICS2 KRT19 KRT34 KRT40 KRT75 KRT76 KRTAP6-2 LCK LGALS14 LHX3 LMO2 LMO3 LMO4 MEOX2 MRPL28 MRPL53 MYEF2 NCK2 NDUFB7 NICN1 NUP54 PATL1 PATZ1 PAX6 PKP1 PLEKHN1 POMC POU4F2 PRDM6 PRMT7 PSMB8 PTCD1 QARS1 RAD51D RBM14 RBM41 RBM4B RFX2 RING1 RTP5 RUNX1 SAMD11 SAMD4A SCNM1 SH2D1B SH3RF1 SLU7 SMAD4 SMG9 SNAPC3 SORBS3 SS18 SSC4D TCF19 TCF4 TCL1A TEKT4 TEKT5 TFIP11 TRAF2 TRIM29 TRIM9 TRIML2 TSEN54 TSSK3 UTP23 VIM ZBTB16 ZC2HC1B ZIC1
Entrez ID		4005	84807
HPRD ID		01586	18140
Ensembl ID		ENSG00000135363	ENSG00000167604
Uniprot IDs		P25791	Q8NI38
PDB IDs		2XJY 2XJZ 2YPA 4KFZ
Enriched GO Terms of Interacting Partners?
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