LMO2 and PATZ1

Data Source:
BioGRID (two hybrid)

		LMO2	PATZ1
Description		LIM domain only 2	POZ/BTB and AT hook containing zinc finger 1
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GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Binding Transcription Coactivator Activity Protein Binding BHLH Transcription Factor Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatogenesis Male Gonad Development Negative Regulation Of Endothelial Cell Migration T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cognitive performance ( 19734545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252)	Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) Height ( 31562340) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		188 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 ARHGEF5 ARID5A ARNT2 AXIN1 BANP BCAS2 BEX2 BLZF1 BYSL C1orf109 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DMRT3 DRAP1 DYDC1 EFHC1 EFHC2 EHMT2 EIF3B EIF4EBP1 ELF2 ENKD1 ERBIN FAAP20 FAM214B FAM228A FAM90A1 FHL3 FHL5 GAS8 GATA1 GATA2 GATA3 GFAP GMEB2 GOLGA2 GRB2 HDAC5 HNRNPC HNRNPM HOOK1 ICA1L IFT43 IHO1 IKZF1 IKZF3 INCA1 ISL1 ISY1 KANK2 KAZN KDM5A KIF2A KIF3B KPRP KRT15 KRT34 KRT40 KRT75 KRT80 KRTAP10-7 LDB1 LDB2 LDOC1 LMO4 LMOD3 LYL1 LZTS1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MISP MRFAP1L1 MSN MTUS2 MYOZ3 N4BP2L2 NCAPH2 NDOR1 NDUFAB1 NDUFB7 NFKBID NHLH1 NIF3L1 NOTCH2NLA NOXA1 NSMF NTAQ1 NUP62 NUTM1 PATZ1 PAX9 PBX4 PDE9A PHC2 POLR2G PPP1R32 PRDM6 PRKG1 PSMA1 RBBP8 RCN1 REL RELA RINT1 RLIM ROCK1 RTL8C RUSC1 SAXO1 SGTB SKP1 SMAD2 SMUG1 SNAPC5 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TBX2 TCP10L TEKT3 TFIP11 TFPT THAP6 TLE5 TLX3 TRIB3 TRIM23 TRIM54 TRIM55 TRIM63 TRIP6 TSC1 TSC22D4 TSEN15 TSEN54 TSGA10IP TSPYL2 TSSK3 TUFT1 UBA6 UBASH3B UBE2I USH1G VBP1 VEZF1 VMAC WASF1 WASHC1 YOD1 YPEL3 ZFP64 ZMYND12 ZNF185 ZNF19 ZNF24 ZNF250 ZNF34 ZNF410 ZNF641 ZNF655 ZNF688	81 interacting genes: AKAP8L BACH1 BACH2 BOLL BPIFA1 C11orf1 C19orf54 CEP76 CLK1 CPSF7 CYSRT1 DAZAP2 DVL3 EYA2 FAM168A FAM168B GOLGA6L9 GPANK1 HNRNPF HNRNPH1 HSPB2 HSPB2-C11orf52 HYI IQUB KLF1 KLHDC7B KRT33B KRTAP12-2 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMO2 LONRF1 LURAP1L LZTS2 MDFI MITF MSX2 NFKBID NHLRC4 OIP5 PFDN5 PHF1 PPP1R16B PPP1R37 PRDM14 PRDM6 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM10 RBPMS RBPMS2 RFX6 RIPPLY1 RNF4 SLAIN1 SMYD1 SPAG8 TLE5 TNS2 TRAF1 TRIP6 TSC1 WWOX WWP2 ZBTB32 ZIC1 ZIM2
Entrez ID		4005	23598
HPRD ID		01586	05522
Ensembl ID		ENSG00000135363	ENSG00000100105
Uniprot IDs		P25791	A0A024R1F8 A0A024R1H7 A0A024R1M5 Q9HBE1
PDB IDs		2XJY 2XJZ 2YPA 4KFZ	2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?
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