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RAD51D and SORBS3
Data Source:
BioGRID
(two hybrid)
RAD51D
SORBS3
Description
RAD51 paralog D
sorbin and SH3 domain containing 3
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Centrosome
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Nucleus
Cytosol
Cytoskeleton
Focal Adhesion
Molecular Function
Four-way Junction DNA Binding
DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Gamma-tubulin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Transcription Factor Binding
Vinculin Binding
Biological Process
Telomere Maintenance Via Recombination
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Repair
Reciprocal Meiotic Recombination
Interstrand Cross-link Repair
Strand Invasion
Regulation Of Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Muscle Contraction
Actin Filament Organization
Cell Adhesion
Cell-substrate Adhesion
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
Smooth Muscle Contraction
Drugs
Diseases
GWAS
Diastolic blood pressure (
30224653
)
HIV-1 viral setpoint (
20205591
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Parkinson's disease (
28892059
)
Interacting Genes
49 interacting genes:
AMOTL2
BLM
C1orf94
CCDC33
CCNL1
CEP57L1
EFHC2
GEMIN4
HSF2BP
IHO1
IKZF1
IKZF3
KATNBL1
KIFC3
KRT15
LIMS1
LNX1
LZTS2
MAPK8IP3
MEOX2
NFKBID
PICK1
PNMA1
POLDIP3
PRDM14
PRDM6
RAD51B
RAD51C
RBM48
REL
RHOU
RNF138
SORBS3
SPATC1L
STX11
SWSAP1
TCF4
TEPSIN
TLE5
TRIM14
TTC23
VPS9D1
XRCC2
XRCC3
ZBTB42
ZC2HC1C
ZNF343
ZNF774
ZSWIM7
133 interacting genes:
ABI2
ABL1
ADAM15
ADAMTSL4
ADAT3
AKIRIN2
AKT2
ANKS1A
ARNT2
C1orf109
CATSPER1
CBFA2T2
CBLB
CCDC102B
CCDC120
CCDC187
CCDC57
CCDC6
CCHCR1
CCNH
CCNL1
CDC23
CDKN2C
CFAP206
CHERP
COG4
CPEB2
CPNE1
CPNE2
CPNE8
CPSF7
CRACR2A
DDX17
DDX6
DIP2A
DLG5
DMRTB1
DVL2
DVL3
EFHC1
EFS
EIF3H
ENKD1
FAM214B
FAM53C
FASLG
FBXL19
FLOT1
FNDC11
GAS8
GEM
GLRA1
GPANK1
GPKOW
GYS1
HGS
HNRNPF
HNRNPK
HNRNPUL1
IMP3
INPPL1
INSC
IQUB
KANK2
KIAA0408
KIAA1217
KIFC3
MAPK1
MAPK3
MKRN3
MYO15B
NAB2
NAF1
NCK1
NCKIPSD
NEK6
NFKBID
NHSL2
NOTCH3
NRBP1
OIP5
OSGIN1
PAK2
PAK5
PHETA1
PHF1
PIBF1
PLEKHN1
PLOD3
PNMA5
POLE2
POLR1C
PPFIA3
PPIL6
PPP1R18
QARS1
RAD51D
RBMX
RIN1
ROPN1
RUNX1T1
SAFB2
SAXO1
SCNM1
SETD5
SH2D4A
SOCS7
SPG21
SRCIN1
SYNPO2L
TBC1D22B
TCEANC
TEAD4
TEPSIN
TNS2
TRIM23
TRIM27
TRIM41
TSGA10
TSGA10IP
TXLNA
USP2
VARS2
VCL
VPS37B
VPS37C
WIPF2
ZBED1
ZBTB25
ZBTB7B
ZC2HC1C
ZC4H2
ZNF414
Entrez ID
5892
10174
HPRD ID
04261
11535
Ensembl ID
ENSG00000185379
ENSG00000120896
Uniprot IDs
O75771
O60504
PDB IDs
2KZ3
2CT3
2DLM
2NWM
2YUP
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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