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RAD51D and RAD51C
Data Source:
BioGRID
(affinity chromatography technology, pull down, affinity chromatography technology)
HPRD
(two hybrid)
RAD51D
RAD51C
Description
RAD51 paralog D
RAD51 paralog C
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Centrosome
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Mitochondrion
Cytosol
Cell Junction
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Rad51C-XRCC3 Complex
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Holliday Junction Resolvase Complex
Molecular Function
Four-way Junction DNA Binding
DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Gamma-tubulin Binding
Four-way Junction DNA Binding
DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Crossover Junction Endodeoxyribonuclease Activity
Biological Process
Telomere Maintenance Via Recombination
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Repair
Reciprocal Meiotic Recombination
Interstrand Cross-link Repair
Strand Invasion
Regulation Of Cell Cycle
Meiotic DNA Recombinase Assembly
Telomere Maintenance Via Recombination
Double-strand Break Repair Via Homologous Recombination
DNA Repair
DNA Recombination
Sister Chromatid Cohesion
Female Meiosis Sister Chromatid Cohesion
Reciprocal Meiotic Recombination
Male Meiosis I
Spermatogenesis
Blood Coagulation
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
Meiotic recombination
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
Fanconi anemia
GWAS
Cognitive function (
25644384
)
Primary tooth development (time to first tooth eruption) (
23704328
)
Testicular germ cell tumor (
23666239
23666240
)
Interacting Genes
49 interacting genes:
AMOTL2
BLM
C1orf94
CCDC33
CCNL1
CEP57L1
EFHC2
GEMIN4
HSF2BP
IHO1
IKZF1
IKZF3
KATNBL1
KIFC3
KRT15
LIMS1
LNX1
LZTS2
MAPK8IP3
MEOX2
NFKBID
PICK1
PNMA1
POLDIP3
PRDM14
PRDM6
RAD51B
RAD51C
RBM48
REL
RHOU
RNF138
SORBS3
SPATC1L
STX11
SWSAP1
TCF4
TEPSIN
TLE5
TRIM14
TTC23
VPS9D1
XRCC2
XRCC3
ZBTB42
ZC2HC1C
ZNF343
ZNF774
ZSWIM7
8 interacting genes:
APP
PALB2
RAD51
RAD51B
RAD51D
SPG21
SWSAP1
XRCC3
Entrez ID
5892
5889
HPRD ID
04261
04143
Ensembl ID
ENSG00000185379
ENSG00000108384
Uniprot IDs
O75771
O43502
PDB IDs
2KZ3
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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