PROP1 and HNRNPF

Data Source:
BioGRID (two hybrid)

		PROP1	HNRNPF
Description		PROP paired-like homeobox 1	heterogeneous nuclear ribonucleoprotein F
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleus Nucleoplasm Cytosol Plasma Membrane Membrane Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Single-stranded RNA Binding Protein Binding TBP-class Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Pituitary Gland Development	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Interleukin-12-mediated Signaling Pathway Regulation Of RNA Splicing
Pathways			FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Phenethyl Isothiocyanate
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS			Antisaccade task score ( 31596458)
Interacting Genes		54 interacting genes: ABHD11 ARSA BATF2 C11orf1 C19orf54 C1orf94 C6orf15 C9orf24 COX6B2 CRYBA1 CYSRT1 DAZAP2 EFEMP2 FAM166A FAM168A HDHD3 HESX1 HNRNPF HOXA1 INTS11 KHDC1 KRTAP13-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP6-3 KRTAP8-1 MAGED1 METTL15 METTL27 NR1D2 OLIG3 OXER1 P4HA3 PITX2 PLEKHB2 POU6F2 PSMB11 PSMB4 RNF144B RNF4 SMUG1 SUMO1 TBX22 TEKT4 TEKT5 TENT5B TINAGL1 TLE5 TMEM42 TRIM42 UBE2I UFSP1 ZNF503	155 interacting genes: AKIRIN2 APOBEC1 ATN1 ATP23 AURKA BBS2 C10orf55 C1orf94 CCDC33 CPSF7 DUX4 DZIP3 EIF4ENIF1 ERG FAM86C1P HNRNPA0 HNRNPD HNRNPH1 HNRNPH3 HNRNPM HNRNPUL1 HSFY1 HSPB1 HYPK IKZF3 INCA1 IQCE KLF1 KLF15 KPRP KRT75 KRTAP7-1 LASP1 LINC01554 LNX1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MRPL17 MSI1 NCBP1 NCBP2 NDRG1 NFKBID NUDT16L1 PATZ1 PDLIM7 POLR2A PROP1 PRPF40A PRR22 PRR32 PRR34 RBFOX1 RBFOX2 RBM4 REL RUSC1 SF1 SF3B4 SLAIN1 SMUG1 SNRPC SORBS3 SPATA8 SUMO2 SUMO4 TENT5B TFG TGM2 TGM7 TLE5 TOE1 TRIB3 TRIM14 TXNL4A UNKL USP54 VAV2 VGLL1 VPS37C YWHAQ ZBTB32 ZNF581 ZNF689 ZNF764
Entrez ID		5626	3185
HPRD ID		03325	03023
Ensembl ID		ENSG00000175325	ENSG00000169813
Uniprot IDs		A0A0G2JQ02 O75360	A0A024R7T3 P52597
PDB IDs			2HGL 2HGM 2HGN 2KFY 2KG0 2KG1 3TFY
Enriched GO Terms of Interacting Partners?
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