PROP1 and ZNF503

Data Source:
BioGRID (two hybrid)

		PROP1	ZNF503
Description		PROP paired-like homeobox 1	zinc finger protein 503
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Metal Ion Binding Repressing Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Pituitary Gland Development	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Neural Precursor Cell Proliferation G1 To G0 Transition Involved In Cell Differentiation
Pathways
Drugs
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS			Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Type 2 diabetes ( 30718926)
Interacting Genes		54 interacting genes: ABHD11 ARSA BATF2 C11orf1 C19orf54 C1orf94 C6orf15 C9orf24 COX6B2 CRYBA1 CYSRT1 DAZAP2 EFEMP2 FAM166A FAM168A HDHD3 HESX1 HNRNPF HOXA1 INTS11 KHDC1 KRTAP13-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP6-3 KRTAP8-1 MAGED1 METTL15 METTL27 NR1D2 OLIG3 OXER1 P4HA3 PITX2 PLEKHB2 POU6F2 PSMB11 PSMB4 RNF144B RNF4 SMUG1 SUMO1 TBX22 TEKT4 TEKT5 TENT5B TINAGL1 TLE5 TMEM42 TRIM42 UBE2I UFSP1 ZNF503	10 interacting genes: ARID5A ATN1 DTX2 FOXH1 KRTAP19-1 KRTAP3-3 KRTAP6-2 PROP1 TENT5B TLE5
Entrez ID		5626	84858
HPRD ID		03325	15811
Ensembl ID		ENSG00000175325	ENSG00000165655
Uniprot IDs		A0A0G2JQ02 O75360	Q96F45
PDB IDs
Enriched GO Terms of Interacting Partners?
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