HNRNPF and NCBP1

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		HNRNPF	NCBP1
Description		heterogeneous nuclear ribonucleoprotein F	nuclear cap binding protein subunit 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Membrane Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Mitochondrion Cytosol MRNA Cap Binding Complex Nuclear Cap Binding Complex RNA Cap Binding Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Single-stranded RNA Binding Protein Binding TBP-class Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Interleukin-12-mediated Signaling Pathway Regulation Of RNA Splicing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription 7-methylguanosine MRNA Capping RNA Catabolic Process RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translational Initiation Histone MRNA Metabolic Process RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Positive Regulation Of Cell Growth Gene Silencing By RNA MRNA 3'-end Processing Positive Regulation Of MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II MRNA Cis Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nuclear Export Pre-mRNA Cleavage Required For Polyadenylation Regulation Of MRNA Polyadenylation Positive Regulation Of RNA Binding
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	SLBP independent Processing of Histone Pre-mRNAs Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Abortive elongation of HIV-1 transcript in the absence of Tat snRNP Assembly RNA Polymerase II Pre-transcription Events FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Intronless Pre-mRNAs Signaling by FGFR2 IIIa TM Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Antisaccade task score ( 31596458)	Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes		155 interacting genes: AKIRIN2 APOBEC1 ATN1 ATP23 AURKA BBS2 C10orf55 C1orf94 CCDC33 CPSF7 DUX4 DZIP3 EIF4ENIF1 ERG FAM86C1P HNRNPA0 HNRNPD HNRNPH1 HNRNPH3 HNRNPM HNRNPUL1 HSFY1 HSPB1 HYPK IKZF3 INCA1 IQCE KLF1 KLF15 KPRP KRT75 KRTAP7-1 LASP1 LINC01554 LNX1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MRPL17 MSI1 NCBP1 NCBP2 NDRG1 NFKBID NUDT16L1 PATZ1 PDLIM7 POLR2A PROP1 PRPF40A PRR22 PRR32 PRR34 RBFOX1 RBFOX2 RBM4 REL RUSC1 SF1 SF3B4 SLAIN1 SMUG1 SNRPC SORBS3 SPATA8 SUMO2 SUMO4 TENT5B TFG TGM2 TGM7 TLE5 TOE1 TRIB3 TRIM14 TXNL4A UNKL USP54 VAV2 VGLL1 VPS37C YWHAQ ZBTB32 ZNF581 ZNF689 ZNF764	18 interacting genes: BNIP1 BNIP2 BNIP3 EIF4G1 EIF4G2 HNRNPF HNRNPH1 LINC01554 NCBP2 NCBP3 PSTPIP1 PTEN RNF20 RNF40 RPS6KB1 SNRPA1 STAU1 ZDHHC17
Entrez ID		3185	4686
HPRD ID		03023	02717
Ensembl ID		ENSG00000169813	ENSG00000136937
Uniprot IDs		A0A024R7T3 P52597	A0A024R179 Q09161
PDB IDs		2HGL 2HGM 2HGN 2KFY 2KG0 2KG1 3TFY	1H2T 1H2U 1H2V 1H6K 1N52 1N54 3FEX 3FEY 5OO6 5OOB 6D0Y
Enriched GO Terms of Interacting Partners?
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