PROP1 and ABHD11

Data Source:
BioGRID (two hybrid)

		PROP1	ABHD11
Description		PROP paired-like homeobox 1	abhydrolase domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Cellular_component Mitochondrion
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Pituitary Gland Development	Biological_process
Pathways
Drugs
Diseases		Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS			Malaria ( 31844061) Total cholesterol levels ( 30498476)
Interacting Genes		54 interacting genes: ABHD11 ARSA BATF2 C11orf1 C19orf54 C1orf94 C6orf15 C9orf24 COX6B2 CRYBA1 CYSRT1 DAZAP2 EFEMP2 FAM166A FAM168A HDHD3 HESX1 HNRNPF HOXA1 INTS11 KHDC1 KRTAP13-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP6-3 KRTAP8-1 MAGED1 METTL15 METTL27 NR1D2 OLIG3 OXER1 P4HA3 PITX2 PLEKHB2 POU6F2 PSMB11 PSMB4 RNF144B RNF4 SMUG1 SUMO1 TBX22 TEKT4 TEKT5 TENT5B TINAGL1 TLE5 TMEM42 TRIM42 UBE2I UFSP1 ZNF503	22 interacting genes: ANKRD11 APP CSTF2 DOK6 DTX2 FNDC3B GCA MDFI MGAT5B MORN3 PITX1 PRKAB2 PROP1 PRR35 RUSC1 USHBP1 VAC14 VENTX VPS37C WWOX YTHDF1 ZIC1
Entrez ID		5626	83451
HPRD ID		03325	15658
Ensembl ID		ENSG00000175325	ENSG00000106077
Uniprot IDs		A0A0G2JQ02 O75360	C9J7Q4 D3DXF2 Q8NFV4
PDB IDs
Enriched GO Terms of Interacting Partners?
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