ARFGAP1 and ASB10

Data Source:
BioGRID (two hybrid)

		ARFGAP1	ASB10
Description		ADP ribosylation factor GTPase activating protein 1	ankyrin repeat and SOCS box containing 10
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Synapse	Nucleus Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification
Pathways		XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Eyebrow thickness ( 26926045) Renal underexcretion gout ( 32238385)
Interacting Genes		34 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	6 interacting genes: AGR3 ARFGAP1 KDM1A LCN2 MEOX2 MRPL23
Entrez ID		55738	136371
HPRD ID		06443	10666
Ensembl ID		ENSG00000101199	ENSG00000146926
Uniprot IDs		Q53F62 Q8N6T3	A0A090N8I2 Q8WXI3
PDB IDs		3DWD 3O47
Enriched GO Terms of Interacting Partners?
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