ASB10 and ARFGAP1

Data Source:
BioGRID (two hybrid)

		ASB10	ARFGAP1
Description		ankyrin repeat and SOCS box containing 10	ADP ribosylation factor GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Golgi Membrane Cytosol Synapse
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Renal underexcretion gout ( 32238385)
Interacting Genes		6 interacting genes: AGR3 ARFGAP1 KDM1A LCN2 MEOX2 MRPL23	34 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23
Entrez ID		136371	55738
HPRD ID		10666	06443
Ensembl ID		ENSG00000146926	ENSG00000101199
Uniprot IDs		A0A090N8I2 Q8WXI3	Q53F62 Q8N6T3
PDB IDs			3DWD 3O47
Enriched GO Terms of Interacting Partners?
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