ARFGAP1 and REEP5

Data Source:
BioGRID (two hybrid)

		ARFGAP1	REEP5
Description		ADP ribosylation factor GTPase activating protein 1	receptor accessory protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Synapse	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport
Pathways		XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis	Olfactory Signaling Pathway
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)
Interacting Genes		34 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1
Entrez ID		55738	7905
HPRD ID		06443	15918
Ensembl ID		ENSG00000101199	ENSG00000129625
Uniprot IDs		Q53F62 Q8N6T3	Q00765
PDB IDs		3DWD 3O47
Enriched GO Terms of Interacting Partners?
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