DPPA4 and CIR1

Data Source:
BioGRID (two hybrid)

		DPPA4	CIR1
Description		developmental pluripotency associated 4	corepressor interacting with RBPJ, CIR1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Cytoplasm Centrosome Nuclear Speck Protein-containing Complex
	Molecular Function	Chromatin Binding Protein Binding	Transcription Corepressor Activity Protein Binding Protein Kinase Binding Histone Deacetylase Binding Protein-containing Complex Binding
	Biological Process	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development MRNA Processing RNA Splicing Negative Regulation Of Transcription, DNA-templated
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)	Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) ( 29899525) Adult body size ( 32376654) Chronotype ( 30696823) Hand grip strength ( 29691431) Triglyceride levels ( 32203549)
Interacting Genes		35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM	14 interacting genes: CCDC33 CEP76 DPPA4 HDAC2 MB21D2 NCOR2 NEK6 RBPJ RP9 SAP30 SNW1 SRSF2 TCEA1 U2AF1
Entrez ID		55211	9541
HPRD ID		16836	05568
Ensembl ID		ENSG00000121570	ENSG00000138433
Uniprot IDs		Q7L190	Q86X95
PDB IDs			6ZYM
Enriched GO Terms of Interacting Partners?
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