DPPA4 and GMPPB

Data Source:
BioGRID (two hybrid)

		DPPA4	GMPPB
Description		developmental pluripotency associated 4	GDP-mannose pyrophosphorylase B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm
	Molecular Function	Chromatin Binding Protein Binding	Mannose-1-phosphate Guanylyltransferase Activity Protein Binding GTP Binding
	Biological Process	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development	GDP-mannose Biosynthetic Process
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Synthesis of GDP-mannose
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Multisite chronic pain ( 31194737) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Resting heart rate ( 27798624) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 21297633)
Interacting Genes		35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM	5 interacting genes: DPPA4 GLYCTK GMPPA POLR1C TXNDC5
Entrez ID		55211	29925
HPRD ID		16836	13589
Ensembl ID		ENSG00000121570	ENSG00000173540
Uniprot IDs		Q7L190	Q9Y5P6
PDB IDs
Enriched GO Terms of Interacting Partners?
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