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THAP1 and DCAF8
Data Source:
BioGRID
(two hybrid)
THAP1
DCAF8
Description
THAP domain containing 1
DDB1 and CUL4 associated factor 8
Image
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
PML Body
Intracellular Membrane-bounded Organelle
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Endothelial Cell Proliferation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Regulation Of Mitotic Cell Cycle
Protein Ubiquitination
Post-translational Protein Modification
Pathways
Neddylation
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Pelvic organ prolapse (moderate/severe) (
26545240
)
Breast size (
27182965
)
Lung function (FEV1/FVC) (
30061609
)
Squamous cell lung carcinoma (
28604730
)
Interacting Genes
105 interacting genes:
ABCF3
ACOT7
AEBP2
AKAP17A
AKAP9
AP2B1
APP
ARL6IP4
BAG5
BEND7
BMS1P1
BYSL
C1orf216
C1orf35
C4orf45
C7orf50
CDC37
CDKN2D
CHD2
CSNK2A1
DCAF8
DVL2
EEF1AKNMT
FAM124A
FAM133A
FAM9A
FGF10
FGF11
FGF12
FXR2
GAS8
GPATCH2L
HNRNPLL
HYPK
INO80B
KANK2
KLF12
KRTAP10-7
L3MBTL2
LASP1
LMNB2
LMO3
LNX1
MFAP1
MIS18A
MORF4L1
MORF4L2
MRPL11
MRPL53
NDUFAB1
NKAP
NKAPD1
NTAQ1
NUP62
PAWR
PHF1
PHF19
PID1
PNKP
POLR2L
POLR2M
POU6F2
PPIG
PRKAA1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QKI
RAD54L2
RALY
RALYL
RBM10
RBM39
RIPPLY1
RNF4
RP9P
RPL22
RPS25
SAP30BP
SERF2
SLU7
SPANXN2
SREK1IP1
STRBP
TCEA2
TCEANC
TPM3
TRAF5
TRIM26
TRIP10
TTLL10
TXN2
U2AF2
UBE2I
VCX2
WT1
YES1
ZBTB48
ZCCHC10
ZGPAT
ZNF385C
ZNF408
ZNF526
12 interacting genes:
DDB1
GTPBP3
MDFI
PIK3R3
PRMT1
PRMT8
RAF1
RBPMS
SUV39H1
THAP1
TNS2
TRIM54
Entrez ID
55145
50717
HPRD ID
15496
18300
Ensembl ID
ENSG00000131931
ENSG00000132716
Uniprot IDs
Q9NVV9
B7Z8C9
Q5TAQ9
PDB IDs
2JTG
2KO0
2L1G
3I8E
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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