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THAP1 and LASP1
Data Source:
BioGRID
(two hybrid)
THAP1
LASP1
Description
THAP domain containing 1
LIM and SH3 protein 1
Image
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
PML Body
Intracellular Membrane-bounded Organelle
Cytoplasm
Focal Adhesion
Cortical Actin Cytoskeleton
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Protein Binding
Ion Transmembrane Transporter Activity
Cadherin Binding
Metal Ion Binding
Actin Filament Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Endothelial Cell Proliferation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Regulation Of Mitotic Cell Cycle
Ion Transport
Ion Transmembrane Transport
Pathways
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Pelvic organ prolapse (moderate/severe) (
26545240
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Interacting Genes
105 interacting genes:
ABCF3
ACOT7
AEBP2
AKAP17A
AKAP9
AP2B1
APP
ARL6IP4
BAG5
BEND7
BMS1P1
BYSL
C1orf216
C1orf35
C4orf45
C7orf50
CDC37
CDKN2D
CHD2
CSNK2A1
DCAF8
DVL2
EEF1AKNMT
FAM124A
FAM133A
FAM9A
FGF10
FGF11
FGF12
FXR2
GAS8
GPATCH2L
HNRNPLL
HYPK
INO80B
KANK2
KLF12
KRTAP10-7
L3MBTL2
LASP1
LMNB2
LMO3
LNX1
MFAP1
MIS18A
MORF4L1
MORF4L2
MRPL11
MRPL53
NDUFAB1
NKAP
NKAPD1
NTAQ1
NUP62
PAWR
PHF1
PHF19
PID1
PNKP
POLR2L
POLR2M
POU6F2
PPIG
PRKAA1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QKI
RAD54L2
RALY
RALYL
RBM10
RBM39
RIPPLY1
RNF4
RP9P
RPL22
RPS25
SAP30BP
SERF2
SLU7
SPANXN2
SREK1IP1
STRBP
TCEA2
TCEANC
TPM3
TRAF5
TRIM26
TRIP10
TTLL10
TXN2
U2AF2
UBE2I
VCX2
WT1
YES1
ZBTB48
ZCCHC10
ZGPAT
ZNF385C
ZNF408
ZNF526
121 interacting genes:
ACD
ACTA1
ACTB
ACTC1
ANKS1A
ARHGEF15
ARHGEF16
ARID5A
ATXN1
BAG4
BAHD1
BHLHE40
C14orf119
C19orf54
CAMK2A
CATSPER1
CDK7
CERCAM
CHERP
COPS5
CRK
CRYBA1
CRYBA2
CSTF2T
CTNNA3
CYSRT1
DAZAP2
DMRT3
DNMT1
DOK6
DTX2
EHMT2
EVX2
FAM168A
FAM168B
FBXO17
FHL3
FOXH1
FXR2
GAS8
GCM2
GOLGA2
GUCD1
HGS
HNRNPF
HOXA1
INTS11
KRTAP10-8
KRTAP12-4
KRTAP19-3
KRTAP19-4
KRTAP19-6
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-2
KRTAP6-2
LENG8
LMO4
LZTS2
MDFI
MED25
MGAT5B
MKRN3
NOXA1
NUTF2
OTX1
OXER1
PITX1
PLSCR1
POLD1
POT1
POU1F1
PPP1R32
PRKAR2B
PRKG1
PRKG2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR35
PSMA3
QRICH1
RBFOX1
RBPMS
RBPMS2
REL
RHOXF2
RNF38
SEPTIN3
SPAG8
SPRY2
STAT3
TCF4
TEKT3
TEKT4
TEKT5
TERF1
TFG
THAP1
TINF2
TLX3
TNS2
TRIM27
TRIP13
UBQLN2
UFSP1
UHRF1
VAC14
VEZF1
VGLL3
VPS37C
WWOX
YES1
YTHDF1
ZBTB9
ZC2HC1A
ZC3H10
ZYX
Entrez ID
55145
3927
HPRD ID
15496
04229
Ensembl ID
ENSG00000131931
ENSG00000002834
Uniprot IDs
Q9NVV9
A0A024R1S8
B4DIC4
Q14847
PDB IDs
2JTG
2KO0
2L1G
3I35
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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