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THAP1 and MFAP1
Data Source:
BioGRID
(two hybrid)
THAP1
MFAP1
Description
THAP domain containing 1
microfibril associated protein 1
Image
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
PML Body
Intracellular Membrane-bounded Organelle
Microfibril
Extracellular Region
Nucleus
Nucleoplasm
U2-type Spliceosomal Complex
Centrosome
U2-type Precatalytic Spliceosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Endothelial Cell Proliferation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Regulation Of Mitotic Cell Cycle
MRNA Splicing, Via Spliceosome
Pathways
Molecules associated with elastic fibres
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Pelvic organ prolapse (moderate/severe) (
26545240
)
Lipoprotein phospholipase A2 activity in cardiovascular disease (
28753643
)
Interacting Genes
105 interacting genes:
ABCF3
ACOT7
AEBP2
AKAP17A
AKAP9
AP2B1
APP
ARL6IP4
BAG5
BEND7
BMS1P1
BYSL
C1orf216
C1orf35
C4orf45
C7orf50
CDC37
CDKN2D
CHD2
CSNK2A1
DCAF8
DVL2
EEF1AKNMT
FAM124A
FAM133A
FAM9A
FGF10
FGF11
FGF12
FXR2
GAS8
GPATCH2L
HNRNPLL
HYPK
INO80B
KANK2
KLF12
KRTAP10-7
L3MBTL2
LASP1
LMNB2
LMO3
LNX1
MFAP1
MIS18A
MORF4L1
MORF4L2
MRPL11
MRPL53
NDUFAB1
NKAP
NKAPD1
NTAQ1
NUP62
PAWR
PHF1
PHF19
PID1
PNKP
POLR2L
POLR2M
POU6F2
PPIG
PRKAA1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QKI
RAD54L2
RALY
RALYL
RBM10
RBM39
RIPPLY1
RNF4
RP9P
RPL22
RPS25
SAP30BP
SERF2
SLU7
SPANXN2
SREK1IP1
STRBP
TCEA2
TCEANC
TPM3
TRAF5
TRIM26
TRIP10
TTLL10
TXN2
U2AF2
UBE2I
VCX2
WT1
YES1
ZBTB48
ZCCHC10
ZGPAT
ZNF385C
ZNF408
ZNF526
90 interacting genes:
ALKBH8
AMOTL2
AP2M1
BEND7
BHLHB9
BICD2
CARD9
CCDC102B
CCDC33
CCDC57
CDC14B
CDCA7L
CEP55
CEP57L1
CEP70
CEP76
COG6
COIL
CSNK2A1
DHX38
DHX8
DNTTIP1
FAM9B
FRA10AC1
FXR1
FXR2
GAS8
GKAP1
GOLGA2
GOLGA6L9
GRIPAP1
HMBOX1
HOMER3
HOOK2
HSF2BP
HSPB1
IK
KATNBL1
KIFC3
KLHL2
KRT40
L3MBTL3
LDOC1
LMNA
LMNB2
LZTS1
MAD1L1
MCRS1
MID2
MIPOL1
MTUS2
NDC80
NGDN
OLIG3
PAX6
PHC2
PIBF1
PIH1D1
PLEKHF2
SART1
SNW1
SSX2IP
STAC3
STX11
TADA2A
TCP10L
TEPSIN
TFIP11
THAP1
TLE5
TRAF2
TRIM41
TRIM42
TRIM54
U2AF1
VPS52
YWHAG
ZBTB1
ZBTB14
ZBTB8A
ZFP1
ZFP41
ZFP64
ZNF398
ZNF41
ZNF558
ZNF620
ZNF71
ZNF76
ZRANB1
Entrez ID
55145
4236
HPRD ID
15496
02569
Ensembl ID
ENSG00000131931
ENSG00000140259
Uniprot IDs
Q9NVV9
P55081
PDB IDs
2JTG
2KO0
2L1G
5F5S
5O9Z
6AHD
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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