IFT57 and YAF2

Data Source:
BioGRID (two hybrid)

		IFT57	YAF2
Description		intraflagellar transport 57	YY1 associated factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Centrosome Cilium Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Ciliary Tip	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Neural Tube Closure Heart Looping Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Regulation Of Apoptotic Process Motile Cilium Assembly Negative Regulation Of Epithelial Cell Proliferation Left/right Pattern Formation Non-motile Cilium Assembly	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 31043756) Regular attendance at a religious group ( 29970889)	Refractive error ( 32231278)
Interacting Genes		8 interacting genes: EXOC5 HIP1 IFT20 SKA2 UBXN10 WASHC1 YAF2 ZDHHC17	29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		55081	10138
HPRD ID		09430	09606
Ensembl ID		ENSG00000114446	ENSG00000015153
Uniprot IDs		Q9NWB7	B4DJQ9 G3V212 Q8IY57
PDB IDs			2D9G
Enriched GO Terms of Interacting Partners?
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