YAF2 and PPP1R11

Data Source:
BioGRID (two hybrid)

		YAF2	PPP1R11
Description		YY1 associated factor 2	protein phosphatase 1 regulatory inhibitor subunit 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Phosphoprotein Phosphatase Activity Defense Response To Gram-positive Bacterium
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lipid metabolism phenotypes ( 22286219)
Interacting Genes		29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42	8 interacting genes: IFT20 LATS1 PPP1CA PPP1CB PPP1CC UBXN2B VCP YAF2
Entrez ID		10138	6992
HPRD ID		09606	09449
Ensembl ID		ENSG00000015153	ENSG00000204619
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	A2BEK1 O60927
PDB IDs		2D9G
Enriched GO Terms of Interacting Partners?
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