IFT57 and SKA2

Data Source:
BioGRID (two hybrid)

		IFT57	SKA2
Description		intraflagellar transport 57	spindle and kinetochore associated complex subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Centrosome Cilium Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Ciliary Tip	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule
	Molecular Function	DNA Binding Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Neural Tube Closure Heart Looping Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Regulation Of Apoptotic Process Motile Cilium Assembly Negative Regulation Of Epithelial Cell Proliferation Left/right Pattern Formation Non-motile Cilium Assembly	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 31043756) Regular attendance at a religious group ( 29970889)	Cognitive function ( 25644384) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239)
Interacting Genes		8 interacting genes: EXOC5 HIP1 IFT20 SKA2 UBXN10 WASHC1 YAF2 ZDHHC17	6 interacting genes: HMOX2 IFT57 PRKD3 RALY SKA1 SPC24
Entrez ID		55081	348235
HPRD ID		09430	13306
Ensembl ID		ENSG00000114446	ENSG00000182628
Uniprot IDs		Q9NWB7	J3KSP0 Q8WVK7
PDB IDs			4AJ5
Enriched GO Terms of Interacting Partners?
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